| Termin | Heim | Gast | Ergebnis |
|---|---|---|---|
| 29.03.25 19:30 | New England Revolution | New York Red Bulls | 2:1 |
| 29.03.25 19:30 | Toronto FC | Vancouver Whitecaps | 0:0 |
| 29.03.25 21:30 | Colorado Rapids | Charlotte FC | 2:0 |
| 30.03.25 00:30 | Atlanta United FC | New York City FC | 4:3 |
| 30.03.25 00:30 | D.C. United | Columbus Crew | 1:2 |
| 30.03.25 00:30 | Inter Miami CF | Philadelphia Union | 2:1 |
| 30.03.25 01:30 | FC Dallas | Sporting Kansas City | 2:1 |
| 30.03.25 01:30 | Chicago Fire | CF Montreal | 1:1 |
| 30.03.25 01:30 | Minnesota United FC | Real Salt Lake | 2:0 |
| 30.03.25 01:30 | Nashville SC | Cincinnati FC | 1:2 |
| 30.03.25 04:30 | San Jose Earthquakes | Seattle Sounders | 1:1 |
| 30.03.25 04:30 | Los Angeles Galaxy | Orlando City | 1:2 |
| 30.03.25 04:30 | San Diego FC | Los Angeles FC | 3:2 |
| 30.03.25 20:15 | St. Louis City SC | Austin FC | 0:1 |
| 31.03.25 01:00 | Portland Timbers | Houston Dynamo | 3:1 |